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How Did People Deal With Pain Before Painkillers?

Imagine the oppressive, suffocating stench of gangrenous flesh and stale sweat filling a dimly lit, damp stone chamber. A man lies strapped to a blood-soaked wooden table, his eyes wide with a primal, unadulterated terror. There are no sterilized instruments here, no softly beeping monitors, and certainly no intravenous drips promising the sweet, numbing oblivion of modern anesthesia. There is only the cold, unforgiving glint of a crude iron blade and the heavy, judgmental silence of the priests watching from the shadows, their crosses gleaming in the candlelight. The surgeon, a burly, unsmiling man whose leather apron is stiff with the rusted crimson of a dozen prior patients, steps forward from the gloom. He offers no comforting words, no reassurances. Modern medicine means that pain relief is as easy as swallowing a quick pill, a concept so profoundly alien to this era that it might as well be magic. But pain has always been a fundamental, inescapable part of human existence, an ever-present demon lurking from the cradle to the grave. So just how did the medievals find ways to push on through the agony?

Because, believe me, they sure needed to. To scream was to show spiritual weakness; to beg for mercy was to question the very will of the Almighty. The human body was a battleground, perpetually besieged by horrific diseases, brutal warfare, and agonizing accidents. Let us travel back in time, leaving our pristine, painless clinics behind, to step into the murky, visceral depths of the Middle Ages. We will pull back the veil on a society that practically worshipped suffering, taking a long, hard look at the deeply rooted internal corruption of a theological medical system, the horrifying yet surprisingly effective use of leech spit, and a desperate, bloody happy accident on a battlefield that forever altered the course of surgical history.

Oh, and whilst you are lending me your ear—and your morbid curiosity—to navigate this dark chapter of human endurance, if you would like to support the channel, we do have extra videos on Patreon and YouTube memberships, as well as a few other special treats. Welcome to Medieval Madness.


By the end of the 10th century, the Christian church had grown to an unimaginable level of influence, becoming an omnipresent force that was even more powerful than kings, seeping into every conceivable corner of medieval life. This absolute authority meant that it was uniquely positioned to push its own unyielding agenda regarding the causes of illness and human suffering. The priests and theologians taught the terrified masses that sickness was never visited on a person by mere chance. There was no concept of microscopic germs or random genetic misfortune. Instead, illness was a direct, targeted blow struck by God himself. It was a divine punishment, deliberately orchestrated to chastise a sinful people, to break their pride, and to brutally bring them back to a state of total obedience.

The church constantly warned from the pulpits that every single man and woman was born into the world already marked by original sin and burdened by inescapable wickedness. It was an invisible, spiritual stain on their soul that only confession, painful penance, and a strict lifetime of unwavering devotion could ever hope to cleanse. The congregation was taught that humans had inherited this dreadful curse from Adam and Eve, the very first man and woman shaped by God’s own hands. Because of their foolish disobedience in the Garden of Eden, they had doomed all of their descendants to be born with that heavy, agonizing original sin.

Church leaders went to great lengths to teach that the physical state of a human body, along with all its grotesque ailments and painful deformities, was a direct, physical reflection of the state of the soul hidden within. It was a terrifying concept: your internal morality was written upon your flesh for the world to see. If a person allowed themselves to give in to the common sins of pride, laziness, or cruelty, then their soul would silently sicken. In response, the body itself would display that spiritual damage, becoming diseased and broken too. In this paranoid worldview, just a common cold, a sniffle, or even a persistent cough could be publicly scrutinized as a definitive sign of inner, moral corruption.

Some medieval theologians, consumed by their own zealous rhetoric, went even further. They vehemently claimed that extreme pain and terminal sickness should not be mourned, but rather greeted as holy gifts, precious trials sent directly by God to test their faith and to serve as a agonizing reminder of how easily His divine grace could turn to terrifying anger. They preached that suffering was the specific tool, the very fire, that Mr. God used to physically purify the soul. Agony burned away the sin, scouring the spirit clean so that after the sweet release of death, those who proved themselves worthy could finally find eternal peace in heaven.

Therefore, according to the strict teachings of the church, those who suffered from the most horrific, flesh-rotting diseases like leprosy were actually said to be uniquely chosen by God. The logic, twisted as it may seem to us today, was that because these poor souls suffered so immensely here on earth, enduring a literal hell among the living, they would be granted salvation much sooner. They would not have to wait around in the fires of purgatory first; their earthly torment had already paid their spiritual debt in full.

The 13th-century French theologian and chronicler Jacques de Vitry passionately championed this idea, even arguing that lepers, despite their terrifying appearance, were actually spiritually superior to other, healthy Christians. He wrote extensively that if these afflicted individuals concentrated solely on doing their penance and accepting their lot, they would absolutely, definitively go straight to heaven, simply because their agonizing suffering had already been completed here on earth. Furthermore, Bernard de Clairvaux, the highly influential co-founder of the legendary Knights Templar, firmly agreed with this theological stance, loudly proclaiming that chronic, incurable disease was nothing short of a divine gift from God. Hey, cheer up Mr. leper, don’t you know you’ll get to heaven sooner? This ideology was not just a fringe belief; it was institutionalized. In the year 1215, Canon 22 of the Fourth Lateran Council—a massive, historic gathering together of the fiercely powerful Pope Innocent III and his loyal bishops—formally, officially, and legally made a direct, unbreakable connection between physical illness and moral sin. From that moment on, illness was indisputably categorized as God’s will. It was an affliction to be endured with silent patience, stoic bravery, and total resignation. It was, above all else, the ultimate test of faith.


While the Church dictated the spiritual meaning of pain, the medical practitioners of the era relied on a system that gave medieval medicine a whole, distinct vibe of its own: humoral theory. This deeply entrenched medical philosophy was based entirely on the four principal elements of the natural world: air, fire, water, and earth. This was not a new invention, but rather an ancient idea carefully inherited from revered ancient Greek philosophers and physicians, specifically giants of history like Hippocrates and Galen.

According to these ancient texts, the human body was essentially a vessel running on four vital, ever-shifting fluids known as humors. Each one of these mysterious liquids was believed to be entirely responsible for maintaining a person’s physical health, their daily mood, and even their overarching personality.

First, there was blood, which was thought to be intrinsically warm and moist. Then came yellow bile, which was categorized as warm and dry. Black bile was considered cold and dry, while phlegm was understood to be cold and moist. These internal fluids directly corresponded to specific personality types, dominating a person’s temperament. The resulting personality types were known, respectively, as sanguine, choleric, melancholic, and phlegmatic.

For a medieval man or woman to remain healthy and pain-free, these four humors had to be perfectly stable and getting along well in harmonious balance. But, if just one single humor was slightly out of balance—whether there was too much or too little of it—then you were in serious trouble. You were immediately deemed in need of aggressive medical attention. The available arsenal to correct these imbalances included dramatic interventions such as bloodletting, severe dietary changes, violent purging of the stomach and bowels, complex herbal remedies, traditional folk healing, and even the whispered, secretive use of magic.

In this medical framework, absolutely any sort of pain was immediately seen as a glaring symptom of a humoral imbalance. Take, for example, the agonizing, universally understood ailment of severe back pain. If a suffering peasant described their affliction to a healer as a cold, damp, heavy ache settling into their bones, the physician would stroke his chin and definitively decide that the pain was caused by a dangerous excess of cold, moist phlegm pooling in the lower back. To counteract this, the healer would logically prescribe intense, warming medicines designed to aggressively heat the area and dry out the moisture, such as painfully hot mustard plasters or steaming, suffocating poultices applied directly to the skin.


Of all the brutal treatments designed to balance the humors, none was more ubiquitous or trusted than bloodletting. Everybody in medieval society, from the most opulent, jewel-draped kings down to the poorest, dirt-stained peasants, believed wholeheartedly in the miraculous, curative properties of letting blood. It was viewed not just as a specific treatment, but as the ultimate cure-all for absolutely everything. There was practically nothing it couldn’t supposedly fix, and that emphatically included the management of severe pain.

To understand just how deeply this belief was ingrained, one only needs to look at the surviving medical literature of the era. One late medieval medical textbook paints a glowing, almost magical picture of the procedure.

“Bloodletting clears the mind, strengthens the memory, cleanses the guts, dries up the brain, warms the marrow, sharpens the hearing, curbs tears, promotes digestion, produces a musical voice, dispels sleeplessness, drives away anxiety, feeds the blood, reads it of poisonous matter, and gives long life. It cures pains, fevers, and various sicknesses, and makes the urine clear and clean.”

To actually perform this miraculous procedure, a barber or a surgeon—often the same person who cut your hair and pulled your teeth—would take a small, terrifyingly sharp iron blade and make a deliberate, deep incision in the terrified patient’s vein. The location of the cut was never random; it had to be made in a very specific place on the body that supposedly corresponded directly to their particular illness. So, naturally, according to their complex charts, a pounding, blinding headache meant the surgeon had to make a painful cut in the sensitive webbing between the thumb and the finger. If you complained of problems with your liver, the procedure required a deep slice just below the elbow.

Once the vein was opened, the dark crimson blood—often a full pint, and sometimes dangerously more—would freely flow out of the body and be carefully caught in a brass or wooden bowl. Only when the surgeon felt the humors were balanced, or when the patient began to visibly swoon, would a tight, unsterilized bandage be applied to finally stop the bleeding.

 

However, some physicians preferred a slightly more natural, albeit far more unsettling, method of bloodletting and pain relief: they used live leeches. While horrific to modern sensibilities, this was actually rooted in genuine, albeit accidental, scientific efficacy. A leech’s slimy saliva naturally contains a powerful, localized anesthetic. This chemical completely dulls the sensation of their tiny, jagged teeth slicing into the flesh, ensuring that the patient is blissfully unaware of the creature’s presence as it gorges itself on their blood.

Fascinatingly, there is a very real possibility that medieval patients experienced genuine, longer-lasting effects from this eerie treatment. Modern science has actually validated this ancient practice. A comprehensive medical study from the year 2003 definitively found that targeted leech therapy could actually ease severe arthritic joint pain far better than a standard, modern anti-inflammatory drug.

But leeches were incredibly versatile and could also be used for other, highly secretive, and deeply personal needs. The Trotula, a famous, widely circulated 12th-century compendium specifically focused on women’s medicine, health, and cosmetics, contains a rather scandalous prescription for young brides terrified of their wedding night. The ancient text explicitly recommends the careful placement of…

“leeches in the vagina, but take care that they do not go in too far so that blood comes out. That way, a woman’s husband will be deceived into thinking that his bride is a virgin.”

But, you know, as fascinating as medieval marital deception is, that is another story entirely.


While barber-surgeons drained blood to cure headaches, they faced entirely different, unimaginably gruesome challenges on the battlefields of Europe. In the late Middle Ages, the introduction of gunpowder brought a horrific new type of trauma: the gunshot wound. The standard, agonizingly painful medical treatment used to blindly cauterize these shattered, blackened wounds was to forcibly pour scalding, bubbling boiling oil directly into the open flesh.

The brilliant French barber-surgeon, Ambroise Paré, later detailed his horrifying experiences in his renowned book, Journeys in Diverse Places. In this seminal work, he vividly described his traumatic time serving at the bloody, chaotic Battle of Turin in 1536, a brutal conflict fought during the grinding Italian War between the forces of France and Italy. Paré was initially a strict adherent to the accepted medical dogma of his time. Quoting directly from the established authority, John de Vigo, in his first book of wounds in general, Paré noted the terrifying rationale behind the boiling oil.

“Wounds made by firearms partake of poison by reason of the powder, and for their cure, he bids you cauterize them with oil of elder scalding hot mixed with a little treacle.”

Paré, a man of conscience, was deeply conflicted by this barbaric practice. He wrote:

“And to make no mistake, before I would use the said oil, knowing this was to bring great pain to the patient, I asked first before I applied it.”

But fate, operating amidst the mud and blood of Turin, intervened. Amidst the endless stream of broken soldiers, Ambroise completely ran out of his supply of elder oil. Surrounded by screaming men with shattered limbs, he panicked. He had absolutely no other choice but to desperately improvise with whatever meager supplies he had left in his medical tent.

So, working frantically, he came up with a strange, unproven new concoction. He mixed together a soothing paste made entirely of the raw yolks of eggs, fragrant oil of roses, and sticky turpentine. He applied this gentle, cooling mixture to the gunshot wounds of the remaining soldiers, binding them up and hoping for the best.

That night, Paré was consumed by absolute terror. Afraid that his improvised treatment would fail horribly, he documented his dread, writing that he feared he would find…

“The wounded to whom I had not used the said oil dead from the poison of their wounds.”

Ambroise found it utterly impossible to sleep that night, tossing and turning, haunted by the specter of the men he believed he had doomed. He arose at the very crack of dawn, rushing through the encampment to check on his patients. What he discovered was a medical miracle that would change surgery forever. He wrote that he found…

“Beyond my expectation that those to whom I had applied my medicament had but little pain and their wounds without inflammation or swelling having rested fairly well that night.”

The egg and rose oil mixture had soothed the ravaged tissues, while the natural antiseptic properties of the turpentine had held infection at bay. The contrast with the traditional treatment was stark, horrifying, and undeniable.

“However, the others to whom the boiling oil was used I found feverish with great pain and swelling about the edges of their wounds. Then I resolved to never burn thus cruelly poor men with gunshot wounds ever again.”

Despite this incredible, serendipitous breakthrough, the medical establishment was fiercely stubborn. It took a good many long, frustrating years before the gentle, humane treatments like those devised by the brilliant Ambroise were finally accepted and widely used by other surgeons. In fact, it wasn’t until 9 full years after his eye-opening experiences at the Battle of Turin that, in the year 1545, he finally published his groundbreaking first book, The Methods of Curing Wounds Caused by Arquebus and Firearms. (An arquebus, for context, being a heavy, incredibly destructive type of early long gun widely used in bloody conflicts across Europe and the sprawling Ottoman Empire during the 15th century).


For surgeries that couldn’t be avoided, and where simple egg yolks wouldn’t suffice to quell the agony of a saw cutting through bone, medieval physicians turned to chemical oblivion. Detailed, complex descriptions for powerful herbal anesthetics—potent, intoxicating blends of wild medicinal plants—appear in dusty, fragile manuscripts dating from as far back as long before Roman times, continuing well into the dark centuries of the Middle Ages.

Many of these dangerous, sleep-inducing remedies originated in the warm, fertile areas around the Mediterranean basin. It was there that the exotic plants and deadly herbs needed to brew these concoctions naturally grow wild under the hot sun. One such famous recipe, carefully written down around the year 800 by the cloistered monks at the ancient Benedictine monastery in Monte Cassino, near Rome, calls for a terrifyingly potent mixture. The monks combined raw opium, toxic henbane, sweet mulberry juice, wild lettuce, deadly hemlock, mystical mandragora root, and even common creeping ivy.

Quite obviously, these highly toxic ingredients needed to be painstakingly measured and mixed together by a very, very skilled, incredibly knowledgeable apothecary. If the ratios were even slightly off, if the hemlock was too fresh or the opium too raw, the suffering patient could be rather easily, and completely accidentally, poisoned to death on the operating table before the surgeon even raised his knife.

By the time human history marched forward to reach the late Middle Ages, these sort of dangerous, sleep-bringing recipes had slowly migrated across the continent and successfully reached the shores of Britain. There, we find countless remedies for a legendary, intoxicating drink named dwale meticulously recorded in several surviving English medical manuscripts. A typical, chillingly precise recipe for this medieval anesthesia reads as follows:

“How to make a drink that men call dwale to make a man sleep whilst men cut him. Take three spoonfuls of the gall bile of a barrow swine for a man and for a woman of a gilt three spoonfuls of hemlock juice, three spoonfuls of wild neep, three spoonfuls of lettuce, three spoonfuls of page, three spoonfuls of henbane, and three spoonfuls of isole and mix them all together and boil them a little and put them in a glass vessel well stopped and put therefore three spoonfuls into a bottle of good wine and mix it well together. When it is needed let him that shall be cut sit against a good fire and make him drink thereof until he fall asleep and then you may safely cut him. And when you have done your cure and will have him awake take vinegar and salt and wash well his temples and his cheekbones and he shall awake immediately.”

If we dissect this ancient potion, we find a terrifying pharmacological cocktail. As well as the heavy base of strong alcohol, there were exactly seven other distinct ingredients floating in a typical batch of dwale. This included the foul-tasting animal bile, wild lettuce, sharp vinegar, and toxic bryony root—elements which, while completely disgusting to consume, are for the most part perfectly harmless to the human body.

But it is the second, shadowy group of ingredients—the heavy opium, the lethal hemlock, and the maddening henbane—that are tremendously powerful, deeply narcotic, and incredibly dangerous. To put this into a modern, terrifying perspective: just 1 single milliliter of pure hemlock juice carries enough toxic potency to be completely deadly to an adult human. Furthermore, with about 3.5 milliliters of raw opium mixed into the draft, the medieval concoction would have been very near to, and practically could have easily exceeded, a fatal, lethal dose. The same holds true for a similar, unregulated amount of henbane. This sobering chemical reality just goes to show exactly how incredibly risky and life-threatening these early, desperate attempts at surgical anesthetics could actually be.

Yet, historically speaking, the infamous dwale may not have been nearly as universally deadly as you might immediately think. The survival rate came down to botany and geography. In the colder, rainier climates of northern Europe, the specific plants used in such potent herbal remedies were often grown especially in enclosed monastic gardens so that they could be cultivated exactly when needed. Because of the lack of intense heat, they were naturally far less chemically potent than their wild cousins grown in the sunnier, harsher weather of southern Mediterranean countries.

Furthermore, as any herbalist knows, a plant is at its absolute strongest and most toxic when it is freshly gathered from the soil. The mandatory medieval process of heavily boiling the mixture, followed by the long-term storage of the dried herbs in glass vessels, would have naturally broken down and severely reduced much of their lethal medicinal impact.

We also have to consider the dosage. A “potel” of wine, as mentioned in the old texts, is roughly around the exact same volume as three modern bottles of wine today. So, what is vitally more important to the survival of the patient is the specific instruction hidden within the recipe itself: it calls for the terrified patient, the one that shall be cut, to sit by the fire and drink from the bottle until he falls asleep. It’s highly unlikely that the groggy, heavily intoxicated patient would have successfully drunk the full, massive amount of the opium-laced wine before passing out.

But, in the end, who really knows? Every single human person is entirely different as to exactly how much strong alcohol and raw narcotics they can physically tolerate before entirely passing out. And it is exactly that terrifying, unpredictable uncertainty in the dosage that made the administration of dwale so dangerously, fundamentally unreliable. You never truly knew if the patient was simply sleeping through the amputation, or if they had quietly slipped away into eternity.

These brutal treatments, these desperate mixtures of pig bile and deadly nightshade, stand as a haunting, undeniable reminder of the harsh, unforgiving reality and the sheer precariousness of medieval life. It was an age of agony, existing long, long before the miraculous discovery of the targeted antibiotics, the sterile antiseptics, and the safe, reliable painkillers that we so completely take for granted and rely on every single day in the modern world.

Yet, amidst all the bloodletting, the boiling oil, and the toxic potions, it is incredibly good to note that the medievals, in their own strange way, genuinely liked to look after their patients. They possessed a deep, intuitive empathy and were surprisingly aware of the healing power of simple relaxation techniques to help comfort the sick and help them find sleep when they were feeling poorly. The great Ambroise Paré, the man who banished boiling oil from the battlefield, beautifully described a gentle, almost poetic technique that he highly recommended for soothing a patient suffering from a severe, pounding headache.

As well as using cool, soft, warm cloths placed gently on the burning forehead, heavily dipped in fragrant, sweet-smelling rosewater, he offered a brilliant, auditory prescription. He said:

“And we must make artificial rain pouring water from some high place into a cauldron that he may hear the sound of it in that way sleep shall be provoked on him.”

A dark room, the scent of roses, and the gentle, rhythmic sound of falling water. After the horrors of the surgeon’s knife and the terror of the apothecary’s dwale, that actually sounds truly delightful.